27th National Clinical Education Symposium Presentation Abstracts

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30 APRIL 2025, WEDNESDAY
10.30-11.45 ORAL PRESENTATION SESSION - 12

Are Adverse Childhood Experiences Associated with Metabolic Syndrome in Patients with Schizophrenia and Bipolar Disorder?

Merve Çelik Özer1, Sahide Nur Nurıpek Melez2, Şeyma YAŞAR3, Neslihan Cansel1

1. İnönü University, Faculty of Medicine, Department of Psychiatry, Malatya
2. Gaziantep University, Faculty of Medicine, Department of Internal Medicine, Gaziantep
3. İnönü University, Department of Biostatistics and Medical Informatics

DOI: 10.5080/kes27.abs24 Page 45

BACKGROUND AND AIM:Adverse childhood experiences (ACEs) are defined as a set of experiences,including sexual, physical and emotional abuse or neglect,that occur before the age of 18. Studies indicate that approximately one-third of patients with psychosis and 30–50% of those with bipolar disorder have experienced childhood trauma.This study aims to investigate the relationship between ACEs and MetS in patients with schizophrenia (Sch) and bipolar disorder (Bp)
METHODS The study included patients aged 18–65 who had been diagnosed with Bp or Sch followed for at least six months, and visited our outpatient clinic between July and August 2024.Participants completed a sociodemographic questionnaire and the Turkish version of the Adverse Childhood Experiences Scale (ACE-TR). MetS was assessed using the NCEP-ATP III criteria.(MetS will be diagnosed based on the presence of three or more of the following: abdominal obesity, hypertriglyceridemia, low HDL, high blood pressure, and fasting hyperglycemia)The study was approved by our university's ethics committee (2024/6177)
RESULTS ]The study included 27 female (39.71%) and 41 male (22.06%) patients,with a mean age of 43.16±10.78 years. Among them,26 (38.24%) had Sch, and 42 (61.46%) had Bp.MetS was present in 57.1% of Bp and 30.7% of Sch patients.The ACE-TR total scores were significantly higher in patients diagnosed with MetS (p < 0.001). MetS prevalence was also higher in unmarried individuals (p = 0.043) those with a greater number of hospitalizations (p = 0.030) and those with more suicide attempts (p = 0.012)(p < 0.05)
CONCLUSIONS:Our study demonstrated a significant association between ACEs and MetS in Bp and Sch patients.The increasing treatment costs associated with MetS will create a significant burden on the country's economy, leading to a serious deterioration in the quality of life for patients.Therefore, paying attention to patients who experience adverse childhood experiences,providing treatment support,taking measures to reduce risks,will offer significant benefits both individually and socially