27th National Clinical Education Symposium Presentation Abstracts

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28 APRIL 2025, MONDAY
17.00-18.15 ORAL PRESENTATION SESSION - 3

Association Between Autistic Traits and Retrospective Course of Obsessive-Compulsive Disorder

Yunus Akkeçili Dinar1

1. State Hospital,Dinar, Afyonkarahisar, Türkiye

DOI: 10.5080/kes27.abs28 Page 50

BACKGROUND AND AIM:Autistic traits are frequently observed in obsessive-compulsive disorder (OCD) and are associated with disorder severity. This study aims to assess autistic traits in OCD using the Autism Spectrum Quotient (AQ) and examine their relationship with retrospective OCD severity and its reduction following treatment.
METHODS (Ethics Committee Approval must be obtained and the number should be specified.):Individuals diagnosed with OCD at the Dinar State Hospital Psychiatry Clinic were assessed using the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) at their initial visit and follow-ups. Thirty-seven participants (Age: 42.20; Male: 14/37) who continued regular follow-ups and met the inclusion criteria were administered AQ and Y-BOCS at the sixth-month visit. Exclusion criteria included psychotic disorders, bipolar disorder, alcohol/substance use disorder, and significant cognitive impairment. Data were analyzed using repeated measures ANOVA (IBM SPSS v.25). Ethical approval: AFSÜ, 13.12.2024, T-2024/11.
RESULTS:Y-BOCS total scores showed a significant linear reduction over time (p <.001). This reduction correlated with AQ total (p =.005) and Social Skill (p =.019), Attention Switching (p =.010), and Communication (p =.024) subscales. The reduction in the obsession subscale correlated with AQ total (p =.018) and Attention Switching (p =.040), while the reduction in the compulsion subscale correlated with AQ total (p =.002), Communication (p =.012), Social Skill (p =.036), and Attention Switching (p =.003).
CONCLUSIONS:Findings suggest that autistic trait severity in OCD is significantly linked to a less reduction in disorder severity after treatment, with a more pronounced impact on compulsion severity. These findings imply that severe autistic traits may influence treatment response in individuals with OCD. Additionally, the well-established link between OCD treatment resistance and factors such as subtle neurological symptoms, biological factors, and neurodevelopmental disorders suggests that a similar connection may exist between treatment resistance and severe autistic traits.