Although the
practice in the field of psychiatric genetics is only in the early stages of
development, advances in molecular biology have led to research on the genetics
of psychiatric disorders. The number of studies in which molecular biological
techniques are used has increased in Turkey as well as in the rest of the world
in recent years. Genetic research differs from other areas of research in three
respects: i. it involves information about more than one generation; ii.
unintentionally obtained information such as paternity can be provided by
genetic testing; and iii. problems due to prenatal and presymptomatic diagnosis
may occur. For these reasons and as genetic research on mental disorders
requires the collaboration between researchers from different disciplines and
several centers, the ethical codes in this area should be carefully determined.
The aim of this study is to review the major ethical considerations of this
subject. In this regard, “respect for the autonomy of the patient” and
informed consent, which is the major reflection of this issue on clinical
practice, are discussed. The implications of genetic counseling on the informed
consent are reviewed. Three major foci of genetic counseling are examined: the
right to know/right not to know the results of genetic testing; the privacy of
genetic information; and who should provide genetic counseling. For the
standardization of genetic research which will be performed in different centers
in Turkey, a proposal for an informed consent form specifically for that purpose
is presented.