28th National Clinical Education Symposium Presentation Abstracts

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OP-49 Digital Ethical Attitudes Among Medical Students: Physicians’ Use of Social Media - Page 133
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OP-50 Anxiety And Aggression Levels In Patients With Bipolar Disorder With And Without Criminal Involvement - Page 135
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OP-51 The Relationship Between Refusal of Antenatal Screening Test and Mother Fetus Attachment - Page 136
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OP-52 Evaluation of ChatGPT, Gemini, Microsoft Copilot, and Deep Seek's performance in the psychiatry official board exams - Page 137
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OP-53 Cognition, Digital Engagement, and Functioning in Emerging Adults with Depression: Evidence for a Depression-Mediated Pathway - Page 139
Hasan Bakay, Ziya Öksüz

BACKGROUND AND AIM:According to the Regulation on the Implementation of the Law on Private Security Services, candidates applying for armed or unarmed private security positions are required to obtain a medical board report, including a psychiatric evalua - Page 140
Esra NadaroğluKarabük Training and Research Hospital, Zuhal Koç Apaydın

20 APRIL 2026, MONDAY
18:30 - 19:45 OP-48 Personality functioning, mentalization, and symptomatic recovery in accelerated transcranial magnetic stimulation treatment of major depressive disorder: preliminary findings

OP-48 Personality functioning, mentalization, and symptomatic recovery in accelerated transcranial magnetic stimulation treatment of major depressive disorder: preliminary findings

Osman Demirci1

1. Kafkas University, Faculty of Medicine, Department of Psychiatry

DOI: 10.5080/61upk.ozt465 Page 131

BACKGROUND AND AIM:Impairments in personality functioning and mentalization are closely related to depression, yet their treatment response remains understudied. This study investigates changes in these constructs in major depressive disorder patients undergoing accelerated transcranial magnetic stimulation(TMS) treatment.
METHODS (Ethics Committee Approval must be obtained and the number should be specified.):23 patients receiving accelerated TMS treatment targeting the dorsomedial prefrontal cortex were evaluated before and after treatment using Hamilton Depression Rating Scale(HAMD), Beck Depression Inventory(BDI), Level of Personality Functioning Scale–Brief Form 2.0(LPFS-BF 2.0), and Mentalization Scale(MentS). Independent samples t-tests, Pearson correlations, and linear mixed models were applied to examine relationships and pre–post changes in depression(HAMD, BDI), personality functioning(LPFS-BF 2.0), and mentalization(MentS). Istanbul University–Cerrahpasa Clinical Research Ethics Committee approved the study with decision number 1210653, dated 23.01.2025.
RESULTS:No significant differences were found in baseline LPFS-BF 2.0(p=0.15) or MentS(p=0.65) scores when participants were grouped by post-treatment HAMD severity(?8 vs <8). Improvement in HAMD was correlated with improvement in LPFS-BF 2.0(r=0.54, p=0.008), whereas improvement in BDI was correlated with improvement in MentS(r=0.67, p<0.001). HAMD and LPFS-BF 2.0 scores showed significant reductions(21.4?9.1, 29.0?23.6, respectively) with a significant time and measure interaction(F(1,22)=21.57, p<0.001) that implies a reduction in HAMD significantly greater than that in LPFS-BF 2.0. BDI score showed a significant reduction(28.7?17.8), whereas MentS score increased modestly(80.1?82.3) without reaching significance, and a significant time and measure interaction was found(F(1,22)=12.92, p=0.002).
CONCLUSIONS:Baseline LPFS-BF 2.0 and MentS scores did not differentiate between remitted and non-remitted patients. While depressive symptoms show a strong response to treatment, improvements in personality functioning and mentalization are more limited. Correlation between improvements in LPFS-BF 2.0 and HAMD scales underscores the interaction between personality dysfunction and depression, while relationship between changes in mentalization and BDI scores may reflect patients’ capacity to recognize their symptomatology as reported in self-assessment measures. Despite the small sample, these preliminary findings offer valuable insights, warranting research in larger populations. Keywords: personality dysfunction, mentalization, major depressive disorder, transcranial magnetic stimulation