27th National Clinical Education Symposium Presentation Abstracts

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28 APRIL 2025, MONDAY
13:00-14:00 POSTER PRESENTATION SESSION-1

The Role of Autistic Traits in the Course of Panic Disorder: A Retrospective Study

Yunus Akkeçili1

1. Dinar State Hospital, Dinar, Afyonkarahisar, Türkiye

DOI: 10.5080/kes27.abs116 Page 142

BACKGROUND AND AIM:Autism Spectrum Disorder (ASD) research has identified subclinical autistic traits (Broad Autism Phenotype, BAP), which negatively impact quality of life and psychiatric symptoms. Given the avoidance behaviors, sensory processing differences, and social-cognitive deficits in PD, exploring the role of autistic traits in disorder severity is warranted. This retrospective study examines autistic features in PD using the Autism Spectrum Questionnaire (AQ) and their relationship with changes in disorder severity over time.
METHODS (Ethics Committee Approval must be obtained and the number should be specified.):This study employed a retrospective design, utilizing medical records from individuals diagnosed with PD at the psychiatry outpatient clinic of Dinar State Hospital. The Panic Disorder Severity Scale (PDSS) was administered at initial consultation (baseline) and at a one-month follow-up, as recorded in patient files. At the six-month visit, among those who continued regular follow-ups, 51 participants (Age: 42.2±10.2; M/F: 19/32) consented to completing the Autism Spectrum Questionnaire (AQ) alongside PDSS reassessment. Exclusion criteria included past or current psychotic disorders, bipolar disorder, alcohol/substance use disorder, and cognitive impairments affecting questionnaire completion. Data were analyzed using repeated-measures ANOVA in IBM SPSS (v25). Ethics approval: AFSU, 13.12.2024, T-2024/11.
RESULTS:A significant linear reduction was observed in PDSS total scores across three time points (p <.001). AQ Attention Shifting scores were significantly associated with this reduction (p=.042). PDSS Agoraphobia sub-scores also showed significant linear reduction (p <.001), correlating with AQ Total Score (p=.037), Communication (p=.041), Social Skills (p=.045), and Attention Switching (p=.010).
CONCLUSIONS:The findings of this study suggest that the presence of more severe autistic traits may exert differential effects on the treatment resistance of PD, particularly in the domain of agoraphobia. In conclusion, higher autistic trait levels were associated with a less pronounced decrease in treatment in PD severity, particularly in the domain of agoraphobia.