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Meta-Cognitive Ability and Brain Damage in Autoimmune Encephalitis: A Case Report

Francesco CORALLO, Viviana LO BUONO, Lilla BONANNO, Simona DE SALVO,Giuseppa SERGI, Placido BRAMANTI, Silvia MARINO
2018 29(3): 216-219
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Autoimmune encephalitis is an important contributor to rapidly
progressive cognitive and behavioral decline. The purpose of this work
was to evaluate the effects of cognitive rehabilitation in a patient with
autoimmune encephalitis. We also wanted to evaluate the effectiveness
of rehabilitative treatment by monitoring the cognitive and metacognitive
outcomes over a time interval.
We reported a case of 22 year-old female patient with autoimmune
encephalitis, cognitive behavioral impairments, and severe reduction
in metarepresentational capacity. We performed an assessment of
personality, neuropsychological, and meta-cognitive functions at
the beginning of the rehabilitative training. The last evaluation was
performed six months after the discharge from the rehabilitation unit. We
applied a combination of remediation, psycho-educational treatment,
and psychotherapy to improve the knowledge and the empathy of the
patient, to promote the selfcontrol strategies, and to prompt better
behavioral management. Our findings revealed an improvement in the
performance of the individual tests after rehabilitative training.