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Psychosocial Functioning in Euthymic Patients with Bipolar Disorder Type–II and Associated Clinical and Cognitive Factors

Rifat Serav İLHAN, Hilal DEMİREL, Vesile ŞENTÜRK-CANKORUR
2018 29(3): 162-170
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Objective: The aim of this study was to investigate psychosocial functioning
of euthymic Bipolar Disorder Type-II (BD-II) patients and the
association between psychosocial functioning with cognitive functions
and subclinical symptoms. The hypothesis was BD-II patients would
have low level of psychosocial functioning comparing to healthy subjects
and psychosocial functioning would be associated independently
with cognitive dysfunction and subclinical symptoms.
Method: Thirthy-three subjects who met criteria for BD-II according
to Structured Clinical Interview for DSM-IV and thirty-five healthy
subjects were included. Clinical symptoms were assessed by Hamilton
Depression Rating Scale (HDRS), Young Mania Rating Scale (YMRS);
Hamilton Anxiety Rating Scale (HARS); psychosocial functioning was
assessed by Functioning Assessment Short Test (FAST). Neurocognitive
assessment battery was consisted of WAIS-R general information subtest;
Wisconsin Card Sorting Test (WCST) perseverative errors, nonperseverative
errors and category completed subtests; Trail Making Test-B
(TMT-B); Stroop TBAG form; Trail Making Test-A(TMT-A) Auditory
Consonant Trigrams (ACT) ACT; Wechsler Memory Scale Revised
(WMS-R).
Results: Clinical symptoms assessed by HDRS, HARS scores; psychosocial
functioning scores assessed by FAST; neurocognitive functions assessed
by WCST category completed and, TMT-B, Stroop test, TMT-A,
ACT, and WMS-R scores were significantly different between the two
groups. FAST scores were associated with ACT scores in BB-II group.
Conclusion: BB-II patients had cognitive dysfunctions and low level
of psychosocial functioning even in their euthymic states. Working
memory dysfunction was independently associated with psychosocial
functioning of euthymic BB-II patients.